体质量指数对老年髋部骨折术后死亡率及围手术期并发症的影响

    Effect of BMI on mortality and perioperative complications after hip fracture in elderly patients

    • 摘要:
      目的: 探讨体质量指数(BMI)对老年髋部骨折死亡率及围手术期并发症发生率的影响。
      方法: 收集65岁以上髋部骨折病人295例病历资料,根据BMI将病人分为体质量不足组(UW组)30例、正常体质量组(NW组)183例、超重组(OW组)65例和肥胖组(OB组)17例。分析比较不同BMI老年病人髋部骨折术前、术中、术后相关指标。
      结果: 295例病人中,10.85%(32/295)在1年后死亡,21.02%(62/295)发生围手术期并发症。各组年龄、手术时间、围手术期并发症、术后1年死亡率间差异均有统计学意义(P < 0.05 ~ P < 0.01)。以NW组病人作为对照,控制年龄、性别、ASA分级、手术时间等混杂因素后,logistic回归分析显示,BMI为老年髋部骨折病人围手术期并发症和术后1年死亡的独立影响因素(P < 0.05 ~ P < 0.01),其中,OB组发生围手术期并发症概率是NW组的4.31倍(P < 0.05,95%CI:1.28 ~ 7.67),UW组是NW组的3.43倍(P < 0.05,95%CI:1.23 ~ 6.56);UW组病人术后1年死亡风险是NW组的3.75倍(P < 0.05,95%CI:2.25 ~ 6.67)。
      结论: 体质量过轻病人术后1年死亡率增高;与正常体质量病人相比,体质量过轻和肥胖病人发生围手术期并发症的风险亦增高。

       

      Abstract:
      Objective To investigate the effects of body mass index (BMI) on mortality and perioperative complications in elderly patients with hip fracture.
      Methods The medical records of hip fractures in elderly patients over 65 years old were collected in our hospital. According to BMI, the patients were divided into the underweight group (UW group) with 30 cases, normal weight group (NW group) with 183 cases, overweight group (OW group) with 65 cases and obese group (OB group) with 17 cases. The preoperative and intraoperative data of hip fractures in three groups were analyzed.
      Results Among the 295 patients, 10.85% (32/295) cases died after one year, and 21.02% (62/295) cases developed perioperative complications. The differences in the age, operation time, perioperative complications and one-year postoperative mortality rate among three groups were statistically significant (P < 0.05 to P < 0.01). Taking patients in the NW group as the control, after controlling the confounding factors such as age, gender, ASA classification and operation time, the results of logistic regression analysis showed that the BMI was an independent influencing factor of perioperative complications and 1-year postoperative death in elderly patients with hip fractures (P < 0.05 to P < 0.01). The probability of perioperative complications in the OB group was 4.31 times that in the NW group (P < 0.05, 95%CI: 1.28–7.67), and that in the UW group was 3.43 times that in the NW group (P < 0.05, 95%CI: 1.23–6.56). The risk of death one year after surgery in the UW group was 3.75 times that in the NW group (P < 0.05, 95%CI: 2.25–6.67).
      Conclusions The mortality rate of patients with low body weight increases one year after surgery. Compared with patients with normal body weight, the patients with underweight or obese also have an increasing risk of perioperative complications.

       

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