晚期食管癌食管内支架置入、动脉插管灌注化疗分析
Metal stent combined with arterial intubation chemotherapy for advanced esophageal carcinoma
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摘要: 目的: 观察联合运用食管内支架及动脉插管灌注化疗对晚期食管癌的疗效。方法: 透视下定位经口放置自膨式覆膜镍钛合金内支架治疗食管狭窄19例;待患者体质恢复1~2周后,采用Seldinger技术,依肿瘤所在部位分别选择相应的供血动脉插管和造影,根据造影结果选择靶动脉灌注化疗药物。结果: 19例共置入21根内支架,食管癌内支架置入后全部显效或有效;动脉灌注化疗显效4例,有效11例,无效3例,1例化疗1次后失访,总有效率78.9%,未见严重并发症发生。结论: 食管内支架置入术治疗晚期食管癌的近期疗效肯定,结合动脉内灌注化疗两种技术联合运用可提高远期疗效及生活质量。Abstract: Objective: To study the efficacy of metal stent combined with arterial intubation chemotherapy for treatment of advanced esophageal carcinoma.Methods: The self-expanding Ni-Ti memorized alloy stent was placed though the mouth of 19 patients with advanced esophageal carcinoma under fluoroscopic guidance.When the physical condition of the patients recovered 1-2 weeks later,selective arterial intubation chemotherapy was given to the location of the carcinoma with Seldinger method.Results: Twenty-one stents were used in 19 cases.Significant efficacy was obtained in all the patients.Effective arterial intubation chemotherapy was obtained in 4 cases,striking improvement in 11 cases and no response in 3 cases.One was out of contact after the first treatment.The total efficacy rate was 78.9%,with no severe complications.Conclusions: The metal stent for advanced esophageal carcinoma has certain efficacy in near future and can improve the long-term efficacy and the life quality of the patients when combined with arterial intubation chemotherapy.