Abstract: Objective: To explore the protective effects of the inhaled anesthesia on myocardium in non-cardiac surgery patients with ischemic heart disease.Methods: Ninety-six patients with ischemic heart disease treated with other operation were randomly divided into the control group and treatment group(48 cases each group),treatment group were treated with control and inhaled anesthesia,respectively.The effects of whose on the perioperative cardiac event,ischemic event and level of cTnI in patients were compared.Results: The incidence rates of intraoperative hypotension,hypoxemia and using cardiovascular active drugs in treatment group and control group were 31.25%,6.25% and 37.50%,and 43.75%,14.58% and 64.58%,respectively,hypotension and hypoxemia had no significant difference in the incidence rate of intraoperative(P< 0.05),but unilization of cardiovascular cative drugs treatment group was significantly lower than the control group(P< 0.01).The differences of the concentration anomalies of cTnI in treatment group and control group at postoperative 1,2 and 3 days were not statistically significant(P >0.05).The differences of the incidence rate of myocardial ischemic event in treatment group and control group after anesthesia and at postoperative 1,2 and 3 days were not statistically significant(P >0.05).Conclusions: The inhaled anesthesia can reduce the use of cardiovascular drugs,and protect the myocardium in non-cardiac surgery patients with ischemic heart disease,which can be used as the preferred treatment for elderly patients with coronary heart disease.