原位肝移植术后胆道并发症3例分析

Biliary tract complications following orthotopic liver transplantation: an analysis of 3 cases

摘要: 目的:探讨肝移植术后胆道并发症的发生原因。方法:回顾分析3例原位肝移植术后发生胆道并发症患者的临床资料。结果:3例术后发生胆道并发症的时间为1~3个月,供肝冷缺血时间平均为8.5h,热缺血时间为3min;其中1例术后发生巨细胞病毒感染,1例发生急性排斥反应。结论:肝移植术后胆道并发症是多种因素的结果,其中肝动脉供血不足、灌注损伤、缺血再灌注、术后病毒感染及排斥反应是其主要原因。

Abstract: Objective: To explore the causes of biliary tract complication following orthotopic liver transplantation(OLT).Methods: The clinical data of 3 patients suffering from biliary tract complications after OLT were retrospectively analyzed.Results: The biliary tract complications occurred 1 to 3 months after OLT.The mean cold and warm ischemic time were 8.5 hours and 3 minutes respectively.Virus infection occurred in one case and acute rejection occurred in one case after transplantation.Conclusions: Many factors are responsible for biliary tract complications.The main causes are inadequate blood supply,ischemic reperfusion injury,viral infection and rejection.