Abstract: Objective: To explore the clinical effects of the epidural anesthesia in labor analgesia,and its effects on stages of labor and pregnancy outcome of maternal and child.Methods: Two hundred and sixteen natural childbirth puerperas with vaginal delivery,full term,single fetus,vertex presentation and no pregnancy complications and anesthesia contraindications,were randomly divided into the observation group and control group.The labor analgesia in observation group and control group were treated with epidural block anesthesia and non-drug,respectively.The delivery pain,duration of second and third labor,postpartum hemorrhage and Apgar scoring of neonate in two groups were observed.Results: The degree of delivery pain in observation group was significantly lower than that in control group(P<0.01).The expansion speed of cervix in observation group were significantly faster than that in control group(P<0.01).The effect of epidural anesthesia on labor analgesia in observation group was better than that in control group,which could shorten the active stage and third stage of labor(P<0.01).The differences of postpartum bleeding and neonatal Apgar score between two groups were not statistical significance(P>0.05).Conclusions: The epidural anesthesia is an ideal method in labor analgesia,which can accelerate labor progress,and is safe and worthy of spreading.