Abstract: Objective: To explore the characteristics of bone metastasis and to investigate the diagnostic value of radionuclide bone imaging in patients with lung cancer.Methods: Bone metastatic sites,quantity and different pathological types were analyzed retrospectively in 113 cases of skeletal metastases patients with lung cancer in past three years.Results: Among the 113 patients,62.8% patients were multiple bone metastasis.Most metastatic sites were in spine,and others were in rib,pelvis,and skull.Conclusions: Multiple bone metastasis is one of the characters of lung cancer.The thorax and thoracic spine is the most frequent metastatic sites.Bone metastasis of squamous carcinoma was more easily than other types of lung cancer.Radionuclide bone scan is the most sensitive method for the diagnosis of osseous metastasis.All the patients with lung cancer should be performed radionuclide bone scan,which is significant for staging,selecting therapy methods and the evaluating prognosis of the disease.