链激酶静脉溶栓治疗早期急性心肌梗死疗效分析

Effect of intravenous thrombolytic therapy of streptokinase on early acute myocardial infarction

摘要: 目的: 探讨链激酶静脉溶栓治疗急性心肌梗死的疗效。方法: 在心电图监测下,对34例急性心肌梗死患者行链激酶静脉溶栓治疗。结果: 冠脉再通22例,再通率达64.7%;未再通12例,其中病死2例,病死率为16.7%。不同时段溶栓时其并发症发生率明显不同(P<0.005)。结论: 早期溶栓治疗可减少并发症,降低病死率。除1例高龄患者消化道出血外,未见其他严重不良反应。

Abstract: Objective: To observe the efficacy of intravenous thrombolytic therapy of streptokinase on early acute myocardial infarction(AMI).Methods: Thirty-four patients with AMI were treated by intravenous thrombolytic therapy of streptokinase under electrocardiogram monitoring.Results: The coronary reperfusions were observed in 22 cases,with a reperfusion rate of 64.7% and no reperfusion was found in 12 cases.Two patients died,with a mortality rate of 16.7%.The rates of complications during the different stages of thrombolytic therapy were significantly different(P<0.005).No severe side effect was found except that one old patient developed digestive tract bleeding.Conclusions: Early application of thrombolytic therapy to AMI can decrease the complication and mortality rate.