Abstract: Objective:To observe the clinical effects between the CO₂ laser microsurgery and traditional self-retaining laryngoscope in the treatment of throat benign and precancerous lesions.Methods:Forty-two patients with throat benign and precancerous lesions were divided into the CO₂ laser group and common group according to the treatment method,and the clinical effects between two groups were compared.Results:All patients were followed up for 3 months,and the difference of total effective rate between two groups was not statistically significant(P>0.05).One case with laryngeal squamous epithelial dysplasia complicated with vocal cord adhesion in CO₂ laser group recurred,and treated with laser microsurgery again.The postoperative recurrence in two cases with laryngeal squamous epithelial dysplasia,and incomplete closure of vocal cord in 1 case with vocal polyp were found in common group.For other cases,the lesions were completed removed,the throat function was good,and no serious complications occurred.Conclusions:The clinical effect of vocal polyp and precancerous lesions treated with CO₂ laser microsurgery is effective,which can preserve the laryngeal structure and function,is an important means in treating throat disease.The operation method is selected according to the parent's condition.