Abstract: Objective: To evaluate the effect of the teaching reform carried out in medical statistics laboratory courses in preventive medical undergraduates. Methods: A survey was conducted in two classes including 99 students enrolled in Bengbu Medical College majored in preventive medicine. One class served as the experimental group and the other as the control group. TCE was adopted in the experimental classes,and the effect was evaluated by the results of the students'final examination and the questionnaires. Results: The final examination score of the experimental group was obviously higher than that of the control groups (P < 0.01);the survey results showed that the students ability in communication,self-teaching,expression,information-acquisition and problem-solving in the experiment group was higher than that in the control group (P < 0.01). Conclusions: TCE teaching models may stimulate the students'interest in medical statistics laboratory courses and enhance their ability of settling problems in practice.