Abstract: Objective: To summary the experience in handling vascular graft infection.Methods: Eight cases of vascular graft infection were all treated by removing the grafts and debridement.Two of them were received autogenous great saphenous vein graft in the extra-anatomic bypass,and one of them was performed allotopia graft replacement.Results: Three cases had amputation above the knee after removing the grafts and one case undertook Budd-Chiari syndrome radical correction operation.The infection in other cases was controlled and the wound healed.No patients died.Conclusions: Application of variant therapeutic measures to graft infection may acquire satisfactory clinical effect.