李晓红, 金钟. 氯诺昔康切口浸润用于术后镇痛临床观察[J]. 蚌埠医学院学报, 2011, 36(3): 250-252.
    引用本文: 李晓红, 金钟. 氯诺昔康切口浸润用于术后镇痛临床观察[J]. 蚌埠医学院学报, 2011, 36(3): 250-252.
    LI Xiao-hong, JIN Zhong. Clinical observation of postoperative analgesia by incisional infiltration of lornoxicam[J]. Journal of Bengbu Medical College, 2011, 36(3): 250-252.
    Citation: LI Xiao-hong, JIN Zhong. Clinical observation of postoperative analgesia by incisional infiltration of lornoxicam[J]. Journal of Bengbu Medical College, 2011, 36(3): 250-252.

    氯诺昔康切口浸润用于术后镇痛临床观察

    Clinical observation of postoperative analgesia by incisional infiltration of lornoxicam

    • 摘要: 目的: 评价氯诺昔康切口浸润用于术后镇痛的可行性及临床效果。方法: 选择头颈部手术患者45例,要求术后镇痛者5例(C组),其余随机分为A组和B组,每组20例。A组:氯诺昔康8 mg溶于0.9%生理盐水20 ml,切口缝合前,由术者注射于切口内各层组织;B组:无特殊处理,直接缝合切口;C组:氯诺昔康48 mg复合舒芬太尼100 μg加0.9%生理盐水至100 ml,术后患者自控静脉镇痛。分别记录各组术后即刻、术后1、6、12、24 h的疼痛评分,观察药物相关副作用、切口愈合情况及患者满意度。结果: A、C组术后各时点疼痛程度明显轻于B组(P<0.01),C组1例发生术后呕吐。3组切口均一期愈合。3组满意度调查均为十分满意或满意。结论: 氯诺昔康切口浸润镇痛效果好,简单易行,可用于浅表小切口手术的术后镇痛。

       

      Abstract: Objective: To evaluate the feasibility and clinical results of postoperative analgesia by incisional infiltration of lornoxicam. Methods: Forty-five patients with head and neck surgery were chosen. Five patients required postoperative analgesia and the remaining were divided into group A and group B with 20 cases each. Group A:8 mg lornoxicam dissolved in 0.9% 20 ml normal saline,before suture,patients were injected by the layers of tissue within the incision; Group B:No special treatment,the incision was sutured directly; Group C:48 mg lornoxicam combined with 100 μg sufentanil dissolved in 0.9% saline to 100 ml, postoperative patient-controlled intravenous analgesia. Record pain score,drug-related side effects,wound healing and patient satisfaction immediately,1,6,12,24 hours after each operation. Results: Pain score of group A, C were significantly lighter than group B (P<0.01),1 case of group C postoperative vomiting. Three wounds were Ⅰ healed. Three satisfaction surveys are very satisfied and satisfied. Conclusions: Lornoxicam promised a good analgesic effect of infiltration and could be used for superficial incision for postoperative analgesia.

       

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