Abstract: Objective: To investigate the safety and effect of early feeding and no nasogastric tube decompression in upper gastrointestinal tract perforation repair. Methods: Thirty-one cases of routine nasogastric decompression were selected randomly as control group,and 28 cases of early feeding and no nasogastric tube decompression selected as trial grpup. The recovery time of bowel sounds,rectal discharge,complication rates of nausea,vomiting,and distention were compared between the two groups. Results: The recovery time of bowel sounds and rectal discharge in trial group was much earlier than that in control group(P < 0.01). Cases of vomiting and distention showed no statisticus difference in two groups (P > 0.05). Conclusions: It is safe and benefictial for the patient's quick recovery to apply early feeding without routine nasogastric decompression for upper gastrointestinal perforation repare.