急性脑梗死患者血清甲状腺激素水平的测定及其临床意义

Detection of serum thyroid hormone level in patients with acute cerebral infarction and its clinical significance

摘要: 目的: 观察急性脑梗死患者血清甲状腺激素水平的变化,并探讨其临床意义。方法: 采用化学发光法检测30例急性脑梗死者和30名健康对照者血清三碘甲状腺原氨酸(T₃)、甲状腺素(T₄)、促甲状腺素(TSH)水平,并对两组进行比较。结果: 急性脑梗死患者血清T₃、T₄、TSH均低于对照者(P<0.01～P<0.001)。结论: 急性脑梗死患者的甲状腺激素水平的改变可能是机体的保护反应,其对疗效观察、估计预后具有一定的指导价值。

Abstract: Objective: To investigate the change of serum thyroid hormone in patients with acute cerebral infarction（ACI）and to explore its clinical significance.Methods: Serum triiodothyronine（T₃）,thyroxine（T₄）and thyroid-stimulating hormone（TSH）were detected by chemoluminescence assay in 30 cases of ACI and 30 normal controls,and the results were compared.Results: The levels of serum T₃,T₄ and TSH were significantly lower in patients with ACI than in those of normal controls（P<0.01 to P<0.001）.Conclusions: The change of serum thyroid hormone in patients with ACI may be a protective reaction in human body,thus treatment that aims to this change is unnecessary.