Abstract: Objective:To investigate the clinical effects of the one-stage resection and anastomosis in the treatment of left colon carcinoma complicated with acute obstruction.Methods:The left colon carcinoma complicated with acute obstruction patients treated with one-staged resection and anastomosis and traditional two-stage anastomosis were divided into the observation group(27 cases) and control group(19 cases),respectively.The postoperative exhaust time,intraoperative blood loss,hospital stay,complications and 3-year survival rate between two groups were compared.Results:The differences of the postoperative exhaust time,intraoperative blood loss,hospital stay and complications between two groups were not statistically signifficant(P>0.05).The 3-year survival rates of observation group and control group were 92.5% and 63.2%,respectively,the difference of which was statistically significant(PConclusions:The one-stage resection and anastomosis in the treatment of left colon carcinoma complicated with acute obstruction is safe and reliable,which can improve the long-term survival rate,and is worth clinical promotion.