Abstract: Objective: To compare the clinical effects of different operation methods in the treatment of late neovascular glaucoma.Methods: Forty-six patients with neovascular glaucoma were randomly divided into A and B groups(23 cases each group).Group A were treated with the ciliary body and peripheral retina condensation technique,group B were treated with the ciliary body and peripheral retina condensation technique combined with trabecular resection of autologous sclera drainage.All cases were followed up for 6 to 12 months.The postoperative intraocular pressure,iris neovascularization,eye shape and complications in two groups were observed.Results: The differences of the control rate of intraocular pressure,fading rate of iris neovascularization and atrophy rate of eyeball between two groups were statistically significant(P<0.05 to P<0.01).Conclusions: The clinical effects of the ciliary body and peripheral retina condensation technique combined with trabecular resection of autologous sclera drainage in the treatment of late neovascular glaucoma are good,which can effectively control the intraocular pressure for a long time,well retain eye appearance,and reduce the postoperative complications.