Abstract: Objective:To explore the effect of hepatobiliary postoperative different analgesia on gastrointestinal motility.Methods:Two hundred and eighteen patients with hepatobiliary operation were divided into 3 groups:75 cases treated with patient-controlled intravenous analgesia(pCIA) acted as groupA,70 cases treated with patient-controlled epidural analgesia(pCEA) as groupB and other 73 cases without treatment as groupC(control group).Gastrointestinal function including onset time of postoperative exhaust and defecation and incidence of nausea and vomiting after operation) and effect of analgesia were measured.Results:The recovery of gastrointestinal function in groupC was faster than that of groupA and B(P＜0.01); onset time of postoperative exhaust in groupA was later than that of groupB(P＜0.01); VAS score in groupC was lower than that of groupA and B(P＜0.01).Conclusions:The effect of analgesia of pCEA and pCIA are similar,and pCEA is more conducive the recovery of gastrointestinal function.