趋化因子受体CXCR7在肝细胞性肝癌组织中的表达及其意义

Clinical significance of expression of CXCR7 in hepatocellular carcinoma

摘要: 目的：探讨趋化因子受体CXCR7在肝细胞性肝癌中的表达及其临床意义。方法：收集54例肝细胞性肝癌患者的癌组织和相应的癌旁组织，采用免疫组织化学方法，检测CXCR7蛋白的表达水平。结果：肝细胞性肝癌中CXCR7蛋白的表达高于癌旁组织(p0.01)，且其表达与淋巴转移、病理分级均有一定关系(p0.05)。结论：CXCR7蛋白的表达与肝细胞性肝癌的进展及淋巴转移有关。

Abstract: To investigate thefour samples of cancer and paraancerousexpression and clinical significance of CXCR7 in hepatocellular carcinoma. Methods:Fifty-tissues of hepatocellular carcinoma patients、、ereprotein was detected by immunohistochemistry. Results:Theexpressionsignificantof CXCR7 protein ofcollected and the expression of CXCR7cancer tissues were significantly higherthan that of paraancerous tissues(p0. O1),which had acorrelationship with lymph node metastasisgrading(p0.05). Conclusions:The expression of CXCR7 protein has a significant correlation with the progressionand pathologicalof hepatocellular. arcinoma and lymph node metastasis