Abstract: Objective:To evaluate the effects of treatment severe multiple trauma patients with gastrointestinal dysfunction with Xuebijing combined with Rhubarb.Methods:Fifty-two severe multiple trauma cases with gastrointestinal dysfunction were randomly divided into treatment group(n=27),which were treated with Xuebijing injection and Rhubarb and control group(n=25),which were not used the above measures.The treatment of original and other disease of two groups were the same.The effects of alleviative gastrointestinal dysfunction and morbidity of multiple organ dysfunction syndrome(MODS) of two groups were observed.Results:The gastrointestinal function scores and morbidity of MODS of the teatment group were significantly lower than that of the control group(P0.01).The effects of alleviative gastrointestinal dysfunction were significantly higher than that of the control group(P0.01).Conclusions:The treatment of Xuebijing combined with Rhubarb have good effects on severe multiple trauma patients with gastrointestinal dysfunction,and can reduce the morbidity of MODS.