Abstract: Objective:To investigate the distribution and correlation of the disinfectants-sulfanilamide drug resistant phenotypes and genotypes in Aciuetobacter baumauuii(Aba) in Zhongshan district.Methods:The senior expert system of VITEK-2 Compact was used to judge the disinfectants-sulfanilamide drug resistant phenotypes in 405 strains Aba from Jan.2010 to Sep.2010,and the qacE△1-sul1 genes were detected by PCR in 30 strains multi-drug resistant Aba.Results:In the phenotypic mode of 405 strains Aba,the phenotypic mode of RESISTANT was 201 strains(49.6%),the phenotypic mode of WILD was 185 strains(45.7%),the phenotypic mode of RESISTANT +WILD was 19 strains(4.7%).In the disinfectants-sulfanilamide drug resistant phenotypes mode of 30 strains Aba,phenotypic mode of RESISTANT was 12 strains Aba,the phenotypic mode of WILD was 15 strains,the phenotypic mode of RESISTANT+WILD was 3 strains.Conclusions:The multiple drug-resistant of the separation Aba is serious,the carrier rate of the qacE△1-sul1 gene is 100%.