沈云玲, 田建卿, 刘耀辉. 3种类型糖尿病前期人群血清抵抗素水平差异及相关危险因素分析[J]. 蚌埠医科大学学报, 2013, 37(4): 404-406.
    引用本文: 沈云玲, 田建卿, 刘耀辉. 3种类型糖尿病前期人群血清抵抗素水平差异及相关危险因素分析[J]. 蚌埠医科大学学报, 2013, 37(4): 404-406.
    SHEN Yun-ling, TIAN Jian-qing, LIU Yao-hui. Serum resistin levels and the correlated factors in three kinds of prediabetes patients[J]. Journal of Bengbu Medical University, 2013, 37(4): 404-406.
    Citation: SHEN Yun-ling, TIAN Jian-qing, LIU Yao-hui. Serum resistin levels and the correlated factors in three kinds of prediabetes patients[J]. Journal of Bengbu Medical University, 2013, 37(4): 404-406.

    3种类型糖尿病前期人群血清抵抗素水平差异及相关危险因素分析

    Serum resistin levels and the correlated factors in three kinds of prediabetes patients

    • 摘要: 目的:探讨3种糖尿病前期人群血清抵抗素水平及相关影响因素。方法:分别测定单纯空腹血糖受损(IFG)、单纯糖耐量减低(IGT)、IGT合并IFG及血糖正常者(NBG)共4组(ni=50)的空腹血清抵抗素水平,并进行比较,分析相关因素。结果:IGT、IFG和IGT+IFG组血清抵抗素水平均高于NBG组(P0.01),IFG组与IGT组差异无统计学意义(P0.05),IGT+IFG组均高于IGT组和IFG组(P0.01和P0.05);logistic回归分析显示,体质量指数、空腹血糖、空腹胰岛素和腹围是血清抵抗素升高的影响因素。结论:3种类型糖尿病前期人群血清抵抗素水平均高于血糖正常人群且升高影响因素为空腹血糖、空腹胰岛素、体质量指数及腹围。

       

      Abstract: Objective:To analyze the serum resistin levels and the correlated factors in three kinds of prediabetes patients.Methods:The fasting serum level of the resistin was examined in patients with impaired fasting glucose(IFG),impaired glucose tolerance(IGT),IGT combined with IFG and in people with normal blood glucose(NBG)(ni=50).The results were compared and analyzed.Results:The fasting serum resistin concentration in the IGT,IFG and IGT+IFG groups was significantly higher than that in the NBG group(P0.01),the difference was not significant between the IFG group and the IGT group(P0.05),the serum resistin level was higher in the IGT+IFG group than that in the IFG and the IGT groups(P0.01 and P0.05).The logistic regression analysis showed that the fasting resistin level was strongly correlated with the fasting serum glucose,fasting serum insulin,body mass index and the waist circumference.Conclusions:The fasting serum resistin concentration in the three kinds of prediabetes patients is higher than that in the NBG group.The fasting resistin level is strongly correlated with the fasting serum glucose,fasting serum insulin,body mass index and the waist circumference.

       

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