董传莉, 谢怀珍, 张兰, 宫芬. 肺炎支原体感染诱发小儿哮喘36例临床分析[J]. 蚌埠医学院学报, 2013, 37(4): 410-411,414.
    引用本文: 董传莉, 谢怀珍, 张兰, 宫芬. 肺炎支原体感染诱发小儿哮喘36例临床分析[J]. 蚌埠医学院学报, 2013, 37(4): 410-411,414.
    DONG Chuan-li, XIE Huai-zhen, ZHANG Lan, GONG Fen. Clinical analysis of children asthma caused by infection of Mycoplasma pneumonia:a report of 36 cases[J]. Journal of Bengbu Medical College, 2013, 37(4): 410-411,414.
    Citation: DONG Chuan-li, XIE Huai-zhen, ZHANG Lan, GONG Fen. Clinical analysis of children asthma caused by infection of Mycoplasma pneumonia:a report of 36 cases[J]. Journal of Bengbu Medical College, 2013, 37(4): 410-411,414.

    肺炎支原体感染诱发小儿哮喘36例临床分析

    Clinical analysis of children asthma caused by infection of Mycoplasma pneumonia:a report of 36 cases

    • 摘要: 目的:探讨肺炎支原体(Mycoplasma pneumoniae,MP)感染诱发的小儿哮喘的临床特征及治疗效果。方法:对74例哮喘发作患儿的临床资料进行回顾性分析,其中MP感染诱发哮喘36例(MP感染诱发组),非MP感染诱发哮喘38例(非MP感染诱发组)。观察2组患儿的发热、咳嗽、喘息、肺部病变、肺外脏器受累情况,以及治疗措施和对支气管扩张剂的治疗反应等。结果:MP感染诱发组患儿在发热、咳嗽、喘息、肺部病变及对支气管扩张剂的反应等方面与非MP组差异均有统计学意义(P0.05~P0.01);2组患儿肺外脏器受累发生率差异无统计学意义(P0.05)。MP感染诱发组应用大环内酯类抗生素治疗效较好。结论:与非MP感染诱发的小儿哮喘比较,MP感染诱发哮喘发热多见、咳嗽剧烈、喘息出现晚且持续时间长,对支气管扩张剂不敏感,大环类酯类抗生素联合支气管扩张剂和糖皮质激素吸入治疗有效。

       

      Abstract: Objective:To explore the clinical characteristics of children asthma caused by infection of Mycoplasma pneumonia(MP) and treatment effect of such diseases.Methods:The clinical data of 74 cases diagnosed as asthma were analyzed retrospectively from 2009 to 2011.Thirty-six cases were diagnosed as asthma caused by infection of MP(infection of MP group) and 38 cases of asthma caused by non-infection of MP(non-infection of MP group).The patients'fever,cough,wheezing characteristics,lungs' function,organs involved extra pulmonary organs,therapies and the treatment responses to bronchodilators were observed.Results:The two groups showed statistical differences in the measures of fever,wheezing characteristics,lungs'function and the treatment responses to bronchodilators(P0.05-P0.01).The incidence of lung involvement was not statistically significant(P0.05).Macrolide antibiotics must be used in the children asthma caused by infection of MP.Conclusions:Compared with non-infection of MP group,infection of MP group has more fever,severe cough with late wheezing for a long time and insensitivity to bronchodilators.The use of macrolide antibiotics along with bronchodilators and inhaled corti-costeroids is effective in the treatment.

       

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