Abstract: Objective: To investigate the effect of precise filtering infusion in reducing the infusion reaction and phlebitis induced by anti-cancer adjuvant drugs.Methods: A total of 306 cancer patients receiving intravenous infusion of anti-cancer adjuvant drugs were randomly divided into observation group(150 cases) and control group(156 cases).The patients in the observation group used disposable precise filtering infusion apparatus and the patients in the control group ordinary syringe injection.The incidence of infusion reaction and phlebitis in the two groups was observed and compared.Results: The total incidence of infusion reaction was 6.7% and 21.1% in the observation group and the control group,respectively;the total incidence of phlebitis was 7.3% and 26.9% in the observation group and the control group,respectively.The incidence of infusion reaction and phlebitis in the observation group was significantly lower than that in the control group(P<0.05 to P<0.01);the phlebitis in the observation group was relieved significantly(P<0.01).Conclusions: Application of precise filtering infusion apparatus can effectively reduce the occurrence of infusion reaction and phlebitis induced by intravenous injection of anti-cancer adjuvant drugs.