张家美, 吴晓蓉, 付英杰, 陈翔, 谢春毅. 稳心颗粒对急性冠状动脉综合征患者心律失常的防治及对血管紧张素Ⅱ的影响[J]. 蚌埠医科大学学报, 2012, 36(6): 687-689.
    引用本文: 张家美, 吴晓蓉, 付英杰, 陈翔, 谢春毅. 稳心颗粒对急性冠状动脉综合征患者心律失常的防治及对血管紧张素Ⅱ的影响[J]. 蚌埠医科大学学报, 2012, 36(6): 687-689.
    ZHANG Jia-mei, WU Xiao-rong, FU Ying-jie, CHEN Xiang, XIE Chun-yi. The effects of wenxinkeli on the arrhythmia of acute coronary syndrome and angiotensin Ⅱ[J]. Journal of Bengbu Medical University, 2012, 36(6): 687-689.
    Citation: ZHANG Jia-mei, WU Xiao-rong, FU Ying-jie, CHEN Xiang, XIE Chun-yi. The effects of wenxinkeli on the arrhythmia of acute coronary syndrome and angiotensin Ⅱ[J]. Journal of Bengbu Medical University, 2012, 36(6): 687-689.

    稳心颗粒对急性冠状动脉综合征患者心律失常的防治及对血管紧张素Ⅱ的影响

    The effects of wenxinkeli on the arrhythmia of acute coronary syndrome and angiotensin Ⅱ

    • 摘要: 目的:观察稳心颗粒对急性冠状动脉综合征(ACS)患者心律失常的预防和治疗作用,以及对血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)的影响。方法:55例ACS患者随机分为2组,对照组27例给予常规治疗,稳心颗粒组28例在常规治疗的基础上予稳心颗粒口服,观察2组心律失常的情况及血AngⅡ的检测结果。结果:稳心颗粒组治疗2周时严重心律失常的发生数少于对照组(P0.05),AngⅡ和B型脑钠肽前体末端肽的浓度与对照组差异均无统计学意义(P0.05),6个月病死率与对照组差异无统计学意义(P0.05)。结论:稳心颗粒对ACS患者的心律失常有治疗作用,且能预防严重心律失常的发生,长期治疗无致心律失常的不良反应,并在治疗2周时对血AngⅡ无显著影响。

       

      Abstract: Objective:To observe the effects of wenxinkeli on the arrhythmia of acute coronary syndrome(ACS) and angiotensin Ⅱ(AngⅡ).Methods:Fifty-five cases with ACS were randomly divided into control group(27 cases) which were treated with conventional medication and treatment group(28 cases) which were treated with conventional medication added to wenxinkeli by oral.The arrhythmia and plasma AngⅡof two groups were observed.Results:The arrhythmia of the treatment group were less than that of the control group(P0.05).The plasma concentration of AngⅡ and N-terminal prohormone of brain natriuretic peptide of two groups had no significant difference at 2 weeks after treatment with wenxinkeli(P0.05).The mortality of two groups had no obviouse difference after 6 months(P0.05).Conclusions:Wenxinkeli can treat arrhythmia,prevent serious arrhythmia and no side-effects in the patients with ACS,which has no influence on plasma AngⅡafter 2 weeks.

       

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