Abstract: Objective: To evaluate the effect of cornesocleral limbus autotransplantation combined with amnion covering and mitomycin C in treatment of recurrent pterygium.Methods: The ulcer polyp in 21 cases(21 eyes) of recurrent pterygium were removed,and then a piece of absorbent cotton containing 0.02% mitomycin C was put on the exposed area of the sclera for two minutes;after fully washed with 0.9% normal saline,the whole surface of the cornea and sclera was covered with a large piece of preserved amnion;the conjunctiva with corneal limbus epithelium was sutured on the limbus above the amnion.All the patients were followed up for three years.Results: The postoperative symptoms in the 21 cases were slight,which disappeared after one week.Two to four weeks later,the amnion was absorbed.The pterygium recurred in two cases during the follow-up period.Conclusions: Cornesocleral limbus autotransplantation combined with amnion covering and mitomycin C is safe and effective for treatment of recurrent pterygium with low recurrences and slight postoperative symptoms.