Abstract: Objective: To explore the clinicopathological features of the cervical acetowhite epithelium and its significance.Methods: Cone biopsy by colposcope was performed in seven hundred women who were positive results for naked eye visual inspection with acetic acid on the uterine cervix.The clinical and pathological data were reviewed.Results: One hundred and twenty-one cervical intraepithelial neoplasia (CIN),including 65 cases of CIN1,28 cases of CIN2 and 28 cases of CIN3,7 squamous cell carcinoma,471 inflammation,34 squamous metaplasia,64 hyperplasia and 3 normal mucosa were diagnosed by histopathology.Conclusions: Using pathological results from cervical biopsy at acetowhite epithelium areas under colposcope as the final diagnosis may correctly guide the screening,diagnosis and treatment for precancerous cervical lesions and carcinomas.