Abstract: Objective:To explore the application and clinical effect of the nasal packing materials in functional endoscopic sinus surgery.Methods:Totally 120 patients were observed,in which,sorbalgon group was 43 cases,sorbalgon add merocel group 30 cases and vaseline gauze group 47 cases.The packing materials were removed after 24 hours.The efficacy of nasal packing materials was assessed in terms of the levels of nasal pain or headache in the leaving period and nasal bleeding after remaval of nasal packing,and the levels of the mucosa swelling 2 weeks later.Results:The incidence rate of nasal severe pain or headache in sorbalgon group,sorbalgon add merocel group and vaseline gauze group was 2.33%,6.67% and 40.42%,respectively.The incidence rate of severe nasal bleeding after removed was 6.98%,10.00% and 25.53%,respectively.The incidence rate of the levels of the mucosa swelling 2 weeks later was 9.30%,10.00% and 21.28%,respectively.The significant statistical difference was observed between the 3 groups(P0.01).Conclusions:The combination of both sorbalgon and merocel can controll bleeding to the lowest,and reduce the edema degree of nasal mucous membrane,and the recovery time.