Abstract: Objective:To explore the effects of Three in One full health guide on the knowledge,belief and practice(KBP) and standard medicine behavior of the elderly with tuberculosis(TB).Methods:Forty-one elderly with TB were investigated by using the method of convenience sampling and self-made questionnaire about KBP of TB's control.According to the results of the questionnaire,the weakness of KBP and the features of illness were analysed and Three in One full health guide were conducted.Medication behavior of all patients were followed up three months after discharge and the KBP of patients were investigated again.Results:Three months after their discharge，the average scores of KBP and passing rate(57.814.84 and 97.56% respectively) of the patients with TB patients were significantly higher than that of the patients entering hospital(31.2411.72,36.59% respectively)(P0.01).During following-up three months after discharge,37 patients took entirely the medicine,3 patients occasionally forgot medication,one changed the type and dosage of drugs and no one frequently forgot or interrupted taking-medication.Conclusions:Three in One full health guide can make the elderly obtain appropriate knowledge,change the attitude of diseases,regulate the patients taking actions and promote health recovery.