Abstract: Objective:To observe the effects of oxygen-driven aerosol inhalation of epinephrine in treatment for children with acute laryngitis.Methods:Fifty two children with acute laryngitis were randomly divided into the treatment group and the control group(26 in each group).The patients in treatment group were treated by inhalation of epinephrine via oxygen-driven nebulizer,and the patients in the control group were inhalated with budesonide.The symptoms and signs of all cases were observed 4 hours after treatment,and the clinical effects were evaluated.Results:The total cure rates of the treatment group and control group were 84.6% and 73.1% respectively,and the differences was not significant(P0.05).Relieving bark-like cough and inspiratory three depressions signs of treatment group were significantly better than that of the control group(P0.05).Conclusions:Oxygen-driven atomizing inhalation of epinephrine can rapidly improve the symptoms of acute laryngitis including bark-like cough and inspiratory three depressions.