Abstract: Objective:To investigate the effects of treatment for refractory postpartum hemorrhage with uterine artery ligation combined with gauze packing in the uterine cavity.Methods:Thirty-nine patients with refractory postpartum hemorrhage during cesarean section were divided into the control group which were treated with the uterine artery ligation combined with modified B-lynch suture(18 cases) and the observation group which were treated with the uterine artery ligation combined with gauze packing in the uterine cavity(21 cases).The methods,indications,time,results and complications of operation of two groups were observed.Results:Twenty-one patients of the observation group were successfully treated,and their uteruses were retained.The 16 patients' uteruses of the control group were retained except 2 patients with the poor hemostatic effect.The amount of hemorrhage in 24 hours in the observation group was less than that in the control group(P0.01).But there were no significant differences between the two groups about hysterectomy numbers,operation time and puerperal morbidity.Conclusions:The effects of treatment for refractory postpartum hemorrhage with uterine artery ligation combined with gauze packing in the uterine cavity is good.The cure is simple and feasible,less bleeding,no complications and adverse effects and can retain uterus.