Abstract: Objective: To investigate the value of ultrasound in the diagnosis of gallstone in fetus.Methods:Twenty-one thousand and twenty pregnant women were prenatally examined by ultrasound,the data of gallstone in 15 fetuses were analysed.Results:Among 15 fetuses,the gestational age of 11 cases,2 cases and 2 cases were closed to,more than and less than normal,respectively.The granular,lumpy and banded strong echo in fetal gallbladder and few posterior echo enhancement were found,which disappeared in 12 cases in 2 weeks and 3 cases in 6 months after birth.Conclusions:Ultrasound can show the strong echo of fetal gallbladder,which has an important value in the diagnosis of fetal gallstone.