伍德生, 吴晓飞. 胰岛素强化治疗急性脑卒中应激性高血糖疗效观察[J]. 蚌埠医学院学报, 2012, 36(9): 1027-1028.
    引用本文: 伍德生, 吴晓飞. 胰岛素强化治疗急性脑卒中应激性高血糖疗效观察[J]. 蚌埠医学院学报, 2012, 36(9): 1027-1028.
    WU De-sheng, WU Xiao-fei. Efficacy of intensive insulin therapy in treatment of stress hyperglyce mia caused by acute cerebral stroke[J]. Journal of Bengbu Medical College, 2012, 36(9): 1027-1028.
    Citation: WU De-sheng, WU Xiao-fei. Efficacy of intensive insulin therapy in treatment of stress hyperglyce mia caused by acute cerebral stroke[J]. Journal of Bengbu Medical College, 2012, 36(9): 1027-1028.

    胰岛素强化治疗急性脑卒中应激性高血糖疗效观察

    Efficacy of intensive insulin therapy in treatment of stress hyperglyce mia caused by acute cerebral stroke

    • 摘要: 目的:探讨胰岛素强化治疗急性脑卒中应激性高血糖的效果。方法:将160例无糖尿病伴有应激性高血糖的急性脑卒中患者随机分成2组,观察组80例,给予胰岛素强化治疗,使血糖控制在4.4~6.1 mmol/L;对照组80例,当血糖11.1mmol/L时,给予常规胰岛素治疗,控制血糖在8.0~11.1 mmol/L。观察2组病死率和感染并发症的发生率及神经功能恢复情况。结果:观察组肺部感染发生率8.75%,尿路感染发生率6.25%,病死率2.50%,均明显低于对照组(P0.01);观察组住院第15、30天的神经功能评分均明显优于对照组(P0.01)。结论:胰岛素强化治疗伴应激性血糖升高的急性脑卒中患者可降低感染发生率和病死率,有利于促进神经功能的恢复。

       

      Abstract: Objective: To investigate the efficacy of intensive insulin therapy in treatment of stress hyperglycemia caused by acute cerebral stroke.Methods: One hundred and sixty nondiabete cases with stress hyperglycaemia caused by acute cerebral stroke were randomly divided into the observation group and control group(80 cases each group) .The observation group were treated with intensive insulin and the levels of blood glucose were controlled at the range of 4.4 to 6.1 mmol /L.The contol group were treated with conventional insulin when the levels of blood glucose were greater than or equal to 11.1 mmol /L and the levels of blood glucose were controlled at the range of 8.0 to 11.1 mmol /L.The mortality, the incidence of infection complication and the neural function recovery of two groups were observed.Results: The incidence of pulmonary and urinary tract infection and mortality of the observation group were 8.75% and 6.25%,and 2.50%, respectively,which were significantly lower than that of the control group(P0.01) .The nerve function scores of the observation group were better than that of the control group on the 15 and 30 days in hospital(P0.01) .Conclusions: Intensive insulin therapy can decrease the mortality and the incidence of infection of acute cerebral stroke complicated with stress hyperglycaemia and promote neural function recovery.

       

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