Abstract: Objective: To explore the surgical method and clinical effect of laparoscopic colorectal-carcinoma surgery. Methods:Fourty-eight cases with colorectal cancer were treated with laparoscopic technique according to the principle of open operation，which included right colon resection in 5 cases， left colon resection in 2 cases， sigmoid colon resection in 4 cases， rectal anterior resection in 20 cases and perineum combined with rectum resection in 17 cases. Results: In 48 cases，1 case with upper rectal carcinoma invasing ureter was converted to open operation. Postoperative recurrent hemafecia in 1 case treated with right colon resection was found，who was stopped bleeding by suturing anastomotic stoma at day 3 after operation， and cured. The time of operation and postoperative intestinal peristalsis recovery were 100 to 190 minutes and 1 to 4 days， respectively. The intraoperative blood loss was 40 to 250 ml. Anastomotic leakage and postoperative urinary retention were not found. Postoperative hospital stay was 7 to 12 days. Fourty-six cases were followed up for 1 to 27 months，1 cases with peritoneal metastases was found in 8 months after operation and 2 patients discharged after 6 months restored after conservative treatment in hospital once again because of adhesive ileus. Conclusions: Laparoscopic colorectal-carcinoma surgery is safe， less trauma， less pain and quick recovery. Skilled laparoscopic technology and rich experience in open colorectal surgery for doctor is the key to the success of operation.