王广川, 赵立, 唐杨章, 王士强. 辛伐他汀治疗慢性肺源性心脏病合并心力衰竭疗效观察[J]. 蚌埠医学院学报, 2013, 37(8): 962-963,966.
    引用本文: 王广川, 赵立, 唐杨章, 王士强. 辛伐他汀治疗慢性肺源性心脏病合并心力衰竭疗效观察[J]. 蚌埠医学院学报, 2013, 37(8): 962-963,966.
    WANG Guang-chuan, ZHAO Li, TANG Yang-zhang, WANG shi-qiang. The effect of simvastatin in the treatment of pulmonary heart disease complicated with heart failure[J]. Journal of Bengbu Medical College, 2013, 37(8): 962-963,966.
    Citation: WANG Guang-chuan, ZHAO Li, TANG Yang-zhang, WANG shi-qiang. The effect of simvastatin in the treatment of pulmonary heart disease complicated with heart failure[J]. Journal of Bengbu Medical College, 2013, 37(8): 962-963,966.

    辛伐他汀治疗慢性肺源性心脏病合并心力衰竭疗效观察

    The effect of simvastatin in the treatment of pulmonary heart disease complicated with heart failure

    • 摘要: 目的:观察辛伐他汀治疗慢性肺源性心脏病(CPHD)合并心力衰竭的疗效。方法:96例CPHD合并心力衰竭患者,随机分为2组,对照组48例,给予常规抗心力衰竭治疗;观察组48例,在对照组治疗的基础上加用辛伐他汀。观察2组治疗效果及血气指标与肺动脉压指标。结果:治疗后观察组血气指标与肺动脉压指标改变均明显好于对照组(P0. 01)。观察组总有效率95. 83%,对照组总有效率75. 00%,2组差异有统计学意义(P0. 05)。结论:辛伐他汀对CPHD合并心力衰竭患者的心功能具有改善作用,在常规治疗的基础上可进一步提高疗效,具有一定的临床应用价值。

       

      Abstract: Objective: To investigate the effects of simvastatin in the treatment of pulmonary heart disease with heart failure. Methods: Ninety-six patients with pulmonary heart disease complicated with heart failure were randomly divided into observation group and control group( 48 cases each group) . The control group were treated with conventional means, the observation group were treated with simvastatin based on the conventional means. The therapeutic effect,blood gas index and pulmonary artery pressure index of two groups were observed. Results: The blood gas and pulmonary artery pressure indexes of the observation group after treatmet were significantly better than those in control group( P < 0. 01) . The total effective rates of the observation group and control group were 95. 83% and 75. 00%, respectively, the difference of which was statistical significance ( P < 0. 05 ) . Conclusions: Simvastatin can improve the heart function in patients with pulmonary heart disease complicated with heart failure and treatment effects,which has certain clinic application value.

       

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