Ⅱb期宫颈癌术前同步放化疗30例疗效分析
The curative effect analysis of preoperative concurrent chemoradiotherapy for 30 cases with Ⅱb cervical cancer
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摘要: 目的:探讨Ⅱb期宫颈癌术前同步放化疗近期临床疗效。方法:将58例组织学明确的Ⅱb期宫颈癌患者分为A组28例,术前给予新辅助化疗;B组30例,术前同步放化疗。比较2组的临床疗效、手术时间、术中出血量、膀胱功能恢复等指标。结果:B组近期临床有效率为90. 00%,高于A组的67. 86%(P0. 05);2组手术时间、术中出血量及膀胱功能恢复时间差异均无统计学意义(0. 05);术前放化疗能降低子宫旁浸润和淋巴结转移率(P0. 05)。结论:术前同步放化疗能提高Ⅱb期宫颈癌近期临床疗效,提高手术切除率,减少子宫旁浸润和盆腔淋巴结转移,是一种可选的治疗方法。Abstract: To explore the curative effects of preoperative concurrent chemoradiotherapy for Ⅱb cervical cancer. Methods:Fifty-eight cases with Ⅱb cervical cancer were divided into group A( 28 cases) and group B( 30 cases) . Group A and B were treated with chemotherapy and concurrent chemoradiotherapy before operation， respectively. The clinical effects，adverse reactions，operative time，blood loss，pathological features and recovery time of bladder function in two groups were analyzed. Results: The clinical effective rate in group B( 90. 00%) was higher than that in group A( 67. 86%) ( P ＜ 0. 05) . The differences of operative time，blood loss and recovery time of bladder function in two groups were not statistical significante( P ＞ 0. 05) . The preoperative chemoradiotherapy could decrease parametrial invasion and pelvic lymphnode metastasis ( P ＜ 0. 05). Conclusions: The preoperative concurrent chemoradiotherapy for Ⅱb cervical cancer can improve the clinical effects and resectable rate and decrease parametrial invasion and pelvic lymphnode metastasis，which is a practicable means.
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