Abstract: Objective: To discuss the effect of PDCA cycle management in the cleaning and disinfection quality in the department of stomatology. Methods: PDCA cycle management( planning， implement， checking and manipulation) was adopted to analyze the problems existing in the cleaning and disinfection room of the stomatology department，and the effects were evaluated. Results: After the application of PDCA cycle management， the cleaning and disinfection quality in the stomatology department was significantly improved;the conformity rate of the apparatus's cleaning，packing and sterilization reached 100. 00%，which was significantly higher than before( P ＜ 0. 05 to P ＜ 0. 01) . Conclusions: PDCA cycle management is effective in improving the cleaning and disinfection quality in the sterilizing room.