不同联合手术治疗翼状胬肉的疗效比较
Clinical comparison of two kinds of surgeries in treatment of pterygium
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摘要: 目的:比较不同联合手术治疗翼状胬肉的临床疗效。方法:将95例(112眼)原发性翼状胬肉患者随机分为丝裂霉素C联合自体角膜缘干细胞移植术组(干细胞组)47例(57眼),以及丝裂霉素C联合羊膜移植术组(羊膜组)48例(55眼)。随访6~18个月,观察2组术眼复发情况。结果:干细胞组复发3眼,复发率5.3%;羊膜组复发13眼,复发率23.6%。2组术后复发率差异有统计学意义(P0.01)。结论:丝裂霉素C联合自体角膜缘干细胞移植术治疗翼状胬肉复发率低,手术安全,疗效可靠。Abstract: ObjectiveTo observe the result of two methods in treatment of pterygium. Methods: A total of 95 patients( 112 eyes) were divided into two groups randomly.Forty-seven patients ( 57 eyes) ( stem cell group) were treated with compound excision which mitomycin C and autologous corneal Limbal stem cell transplantation with conjuctival flap were used.Forty-eight patients( 55 eyes)( amnion group) were treated with mitomycin C and amniotic transplantation.After 6 － 18 months follow-up， the postoperative recurrence and complication of two groups were analyzed.Results: Three cases reoccurred and the recurrence rate was 5.3 % in stem cell group.Thirteen cases reoccurred and the recurrence rate was 23.6 % in amnion group.There was statistical difference in the recurrence between the two groups( P 0.01) . Conclusions: The antologous corneal limbal stem cell transplantation with conjunctiva flap can decrease the recurrent rate， and it is safe， effective， reliable for the treatment of pterygium
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