Abstract: ObjectiveTo summary CT manifestation of secondary pulmonary mycotic infection in leukemia， to improve diagnosis and understanding of the disease. Methods: Analyzed CT findings and clinical data of 25 cases of IPA in leukemia，record image characteristic of the type，distribution，morphology， size，number.Results: In 25 cases， 12 cases of consolidative， single patch in 3 cases，multiple patchy in 9 cases， there are real shadows in 5 cases，bronchial gas phase in 6 cases，5 cases of concurrent single /multiple nodules with hemorrhagic pulmonary infarction; change sign in 15 cases， for pointing toward the hilum，wedge-shaped lesions in the bottom of the pleura，bronchi and gas phase in 9 cases， at the same time to see the small cavity in 3 cases.Mass type: single or multiple nodules or masses in 7 cases，4 cases with patchy lesions， found around the halo sign in 5 cases; see air crescent sign in 2 cases.Six cases of mixed type，also visible above two.Others: Eight cases of adjacent pleural thickening and adhesion，2 cases with calcification. Conclusions: CT findings of IPA in leukemia are various，nodule and halo signand /or wedge consolidation and air bronchogram are the specific manifestation on CT images，which are contributed to diagnose early and reduce misdiagnosis.