Abstract: Objective: To observe the effect of artificial nose in airway humidification of ventilated patients.Methods: One hundred and eight patients using mechanical ventilation were randomly divided into two groups:artificial nose group and routine airway humidification group.The sputum viscosity of the patients was observed,and the effects of the airway humidification were compared between the two groups.Results: The cases with degree Ⅰ sputum accounted for 66.67% and 27.78% in the artificial nose group and the routine airway humidification group,respectively.The difference was significant (P<0.01).Conclusions: The artificial nose can ensure the tracheal humidity and warmth.