Abstract: Objective: To compare the clinical effects of proximal femoral intramedullary nails( PFNA) and minimally invasive percutaneous plate osteosynthesis( MIPPO) in the treatment of intertrochanteric fracture. Methods: Sixty-five cases with intertrochanteric fracture were treated with PFNA( group PFNA) and MIPPO( group MIPPO). The clinical data of operation period index,clinical healing time of fracture,the recovery degree of postoperative hip joint function and postoperative complications of two groups were retrospectively analysed. Results: All patients were followed up for 8 to 25 months. There were not statistical significance in the time of fracture healing and recovery degree of postoperative hip joint function between two groups( P 0. 05). The time of operation and lying in bed,incision length,intraoperative blood loss and hospitalization days of PFNA group were less than those of MIPPO group( P 0. 01). Conclusions: The clinical effects of two kinds of fixed means are similar. PFNA is smaller trauma,less bleeding and shorter time in bed.