Abstract: Objective: To explore the curative effects of microwave endometrial ablation( MEA) in the treatment of abnormal uterine bleeding. Methods: The endometrium of 36 patients with abnormal uterine bleeding was removed by microwave therapy instrument. The curative effects of all patients were followed up. Results: All patients were followed up for 18 months. Amenorrhea in 18 cases, significant improvement in 12 cases,menstrual quantity decreasing in 3 cases,menses non-improvement in 3 cases were found,the total effective rate was 91. 7%( 33 /36). Among 36 patients,10 in 12 cases with obvious dysmenorrhea were improved after operation. The menstruation and haemoglobin quantity of all patients 18 months postoperation were less and higher than those before operation, respectively( P 0. 01). All patients were operated in the outpatient,the operation time was 160- 202 s,and there were no serious complications such as bleeding,infection and uterine perforation. Conclusions: MEA is an effective,safe and simple means in the treatment of abnormal uterine bleeding,especially for these patients with severe medical disease.