The effective comparsion of sufentanil and fentanyl on agitation of children treated with tonsillectomy under sevoflurane anesthesia during the recovery period
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摘要: 目的：比较舒芬太尼与芬太尼用于小儿七氟烷全麻下扁桃体切除术苏醒期躁动的效果。方法：选取七氟烷全麻下扁桃体切除术患儿60例，随机分为A、B、C组，每组20例。B组患儿静脉注射2 μg/kg芬太尼，C组患儿静脉注射0.2 μg/kg舒芬太尼，A组患儿静脉注射等体积的0.9%氯化钠注射液。结果：3组患儿拔管时间和恢复时间差异均无统计学意义（P>0.05）。C组患儿重度躁动发生率均显著低于A组时患儿（P<0.01）。B组和C组患儿插管前和插管后1 min时的心率和血压均显著低于进入手术室时（P<0.01），且均低于A组（P<0.05～P<0.01）。结论：静脉注射舒芬太尼治疗小儿七氟烷全麻下扁桃体切除术苏醒期躁动取得了良好的临床效果，显著降低患儿苏醒期躁动的发生率，并且不会影响患儿的苏醒时间和恢复时间。Abstract: Objective: To compare the therapeutic effects of sufentanil and fentanyl on agitation of children treated with tonsillectomy under sevoflurane anesthesia.Methods: Sixty children treated with tonsillectomy under sevoflurane anesthesia were randomly divided into the A,B and C group(20 cases each group).The group B,C and A were intravenously injected with 2 μg/kg of fentanyl,0.2 μg/kg of sufentanil and the same volume of saline,respectively.Results: The incidence of severe agitation in group C was significantly lower than that in group A(P<0.01).The heart rate and arterial pressure before intubation and at 1 min after intubation were significantly lower than those in entering the operating room in group B and group C,and which was lower than those in group A(P<0.05 to P<0.01).Conclusions: The effects of the intravenous injecting sufentanil on agitation of children treated with tonsillectomy under sevoflurane anesthesia during the recovery period are good,which can significantly reduce the incidence of agitation,and do not affect the time of awakening and recovery of children.
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Keywords:
- anesthesia /
- tonsillectomy /
- sufentanil /
- fentanyl /
- sevoflurane /
- agitation of the recovery period
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