血塞通注射液对腹腔镜胆囊切除术患者凝血功能的影响

    Effect of Xuesaitong injection on coagulation function of patients undergoing laparoscopic cholecystectomy

    • 摘要: 目的: 探讨血塞通注射液对腹腔镜胆囊切除术(LC)患者凝血功能的影响。方法: 将LC患者50例随机分为对照组和血塞通组,每组25例。对照组术后予常规抗感染和补液治疗,血塞通组在此基础上于术后第1天起静脉滴注血塞通,连续6d。在术前及术后3、5、7 d测定患者凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)。结果: 术前2组患者PT、APTT、凝血酶原国际标准化值(INR)差异均无统计学意义(P>0.05);术后7 d 2组PT值差异有统计学意义(P<0.01)。2组PT、APTT、INR手术前后不同时间差异均无统计学意义(P>0.05)。结论: 血塞通注射液可改善手术导致的高凝状态。

       

      Abstract: Objective: To investigate the effects of Xuesaitong injection on coagulation function of patients undergoing laparoscopic cholecystectomy(LC).Methods: Fifty patients with LC were randomly divided into control group and Xuesaitong group(25 cases each group).The control group were treated with conventional anti-infection combined with transfusion.The Xuesaitong group were treated with Xuesaitong based on the control group treatment by intravenous drip at 1 day after surgery once daily for 6 days.The levels of prothrombin time (PT)and activeated partial thromboplastin time (APTT)of all patients were measured in the preoperative and postoperative 3,5 and 7 days.Results: There were not significant difference in the levels of PT,APTT and international normalized ratio(INR)between the two groups before the operation(P > 0.05).There were significant difference in the levels of PT between the two groups at 7 days after operation(P<0.01).There were not significant difference in the levels of PT,APTT and INR of each group at different time points before and after the operation(P > 0.05).Conclusions: Xuesaitong injection can obviously improve the state.

       

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