神经元特异性烯醇化酶检测对颅脑损伤诊断分型及判断预后的临床意义
The effect comparsion of modified proximal femoral nail antirotation with dynamic hip screw in the treatment of femoral trochanter fractures
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摘要: 目的:探讨急性颅脑损伤患者检测血清神经元特异性烯醇化酶(neuRon-specific enolase,NSE)的含量及动态变化,对颅脑损伤的诊断分型、评估伤情和判断预后的临床价值。方法:采用放射免疫法,对185例急性颅脑损伤患者(观察组)及50名健康体检人群(对照组)血清NSE水平进行检测。分别于颅脑损伤后1、3、7、10 d NSE水平进行动态检测和观察。结果:观察组颅脑损伤后1 d血清NSE水平均显著高于对照组(P0.01),与格拉斯哥昏迷评分呈负相关关系(P0.05);动态检测血清NSE水平显示重型颅脑损伤患者虽经积极救治,血清NSE水平均持续高于中型颅脑损伤患者(P0.01)。结论:检测患者颅脑损伤后血清NSE水平可以直接反映脑细胞损害程度,是一项较为敏感的生化指标,特别是动态检测血清NSE水平对判断颅脑损伤后伤情评估、疗效观察及预后具有一定的临床意义。Abstract: Objective:To compare the clinical effects of proximal femoral nail antirotation(PFNA) with dynamic hip screw(DHS) in the treatment of femoral trochanter fractures.Methods:Intraoperative and postoperative complications and postoperative hip joint function recovery of 29 cases treated with PFNA(PFNA group) and 36 cases treated with DHS(DHS group) were analyzed.Results:Compared with DHS group,the time of operation and ambulation and intraoperative bleeding in PFNA group were less(P 0.01).The differences of the healing time of fracture and excellent rate of Harris score in two group were not statistically significant(P 0.05).Conclusions:PFNA is easy operating,less trauma and bleeding and tight fixation.Postoperative patients can early ambulate.PFNA is a ideal means for treating femoral trochanter fractures.
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