恶性腹水中CD8~+CD28~-NRP-1~+T细胞的表达水平及其临床意义
Expression and clinical significance of the CD8 + CD28 - NRP-1 + T cells in malignant ascites
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摘要: 目的：检测恶性腹水中CD8﹢CD28-NRP-1+T细胞的表达水平,并探讨其临床价值。方法：采用流式细胞仪检测24例肝硬化腹水、20例结核性腹水、28例恶性腹水中CD8﹢CD28-NRP-1+T细胞的表达水平。结果:恶性腹水组CD8+CD28-NRP-1+T细胞的表达水平均明显高于肝硬化腹水组及结核性腹水组(P0.01)。结论：CD8+CD28-NRP-1+T细胞的表达水平在良恶性腹水中存在显著差异,可作为判定良恶性腹水的辅助诊断指标。Abstract: Objective: To study the expression and clinical significance of CD8 + CD28 - NRP-1+ T cells in malignant ascites.Methods: Flow cyObjective: Tometry was used Objective: To test the levels of CD8 + CD28 - NRP-1+T cells in hepaObjective: Tocirrhosis ascites(n = 24) tuberculous ascites(n = 20) and malignant ascites(n = 28). Results: The positive expression rate of CD8 + CD28 - NRP-1+ T cells in malignantascites was significantly higher than that in hepaObjective: Tocirrhosis ascites and tuberculous ascites(P ＜ 0. 01). Conclusions: The expression of CD8 + CD28 - NRP-1 + T cells is significantly different between benign and malignant ascites， and can be used Objective: To distinguish benign and malignant ascites.
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