Abstract: Objective: To explore the clinical effect of bi-level positive airway pressure (BiPAP ) respiraObjective: Tor combined with aerosolization inhalation in the treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)accompanied by type Ⅱ respiraObjective: Tory failure. Methods: Sixty-eight elderly patients with AECOPD accompanied by type Ⅱ respiraObjective: Tory failure were randomly divided inObjective: To control group(33 cases) and experiment group(35 cases). The control group were given the routine therapy such as antibiotics，cleaning the airway and BiPAP ventilaObjective: Tor，and the experiment group were given inhalation of terbutaline sulfate and budesonide in addition. The changes of the clinical manifestation， arterial blood gas analysis before and after treatmen， and the time of hospital stay were compared between the two groups. Results: The clinical manifestation and blood gas analysis of the two groups improved significantly after the therapy(P ＜ 0. 05 Objective: To P ＜ 0. 01) ; the average hospital stay of the experiment group was much shorter than that of the control group(P ＜ 0. 01). Conclusions: BiPAP ventilation combined with aerosolization inhalation is effective on elderly patients with AECOPD accompanied by type Ⅱ respiraObjective: Tory failure.