急性期间日疟患者血浆-干扰素和白细胞介素-17水平分析
The plasma levels of interferon-gamma and interleukin-17 of the acute stage in patients infected with Plasmodium vivax
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摘要: 目的:分析急性期间日疟患者血浆中-干扰素(IFN-)和白细胞介素-17(IL-17)水平。方法:用酶联免疫吸附方法检测19名急性期间日疟患者(间日疟组)和20名健康志愿者(对照组)血浆中IFN-、IL-17水平。结果:间日疟组患者血浆中IFN-和IL-17水平分别为(18.866.77)pg/ml和(41.4621.03)pg/ml,均明显高于对照组的(9.998.78)pg/ml和(25.2311.83)pg/ml(P0.01)。结论:间日疟患者血浆中IFN-和IL-17的水平均升高。Abstract: Objective:To investigate the plasma levels of interferon-gamma( IFN- ) and interleukin-17(IL-17) of the acute stage in patients infected with Plasmodium vivax. Methods:The plasma levels of IFN- and IL-17 in 19 patients infected withPlasmodium vivax (Plasmodium vivaxgroup) in acute stage and 20 healthy people(control group) were measured using enzyme-linked immunosorbent assay. Results:The plasma levels of IFN- and IL-17 in Plasmodium vivax group(18. 86 6. 77)pg/ml and(41. 46 21. 03) pg/ml were significantly higher than those in control group(9. 99 8. 78)pg/ml and(25. 23 11. 83)pg/ml(P 0. 01). Conclusions:The plasma levels of IFN- and IL-17 of patients infected with Plasmodium vivax were increased.