Abstract: Objective: To explore the optimal management of idiopathic thrombocytopenic purpura(ITP) in pregnancy.Methods: The data of 18 cases of ITP in pregnancy were studied retrospectively.For the patients with ITP,prednisone or intravenous immunoglobulin(IVIG) was the first choice.Short-term platelet transfusion was given to those with platelet count less than(50×10⁹/L).Results: Among the 18 cases,vaginal delivery and cesarean section were performed in 6 and 12 cases,respectively;the occurrence of postpartum hemorrhage was 11.1%.No maternal death occurred,and no neonatal thrombocytopenic was observed.Conclusions: We must reinforce obstetrical surveillance and management of ITP in pregnancy.We suggest that ITP mothers without obstetrical complications adopt vaginal delivery.Cesarean delivery should be performed to those whose platelet count is less than 50×10⁹/L or with other obstetrical complications when there is sufficient fresh blood and platelet.