Abstract: Objective:To explore the role of duodenoscope in treatment of residual and recurrent extrahepatic bile duct stones after cholecystectomy and choledochotomy.Methods:The clinical data of 31 patients undergoing duodenoscopic treatment for residual and recurrent extrahepatic bile duct stones were analyzed retrospectively.Results:All the 31 cases were diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and treated by endosopic sphincterotomy (EST).Thirty out of 31 cases (96.8%) were cured.After operation,1 case was converted to open operation because of cholangitis,2 cases had slight bleeding and 4 cases got a transient increase in serum amylase.Conclusions:ERCP is of great value in diagnosis of recrudescences of commonbile duct stones and operational complications.EST is an effective means in non-operation treatment of extrahepatic bile duct stones.