Abstract: Objective: To investigate the way of fetal macrosomia delivery and the supervision,investigate the relevant factors for macrosomia diagnosis and to reduce the complications of mothers and infants.Methods: The clinical data of 240 macrosomia fetuses,and 240 pregnant women who delivered mature and natural fetus as the control group were reviewed and analyzed.Results: The occurrence of macrosomia fetus was related to the overweight of the pregnant women,accompanied diabetes,hereditary factors,excessive intake of food for the women and too little exercise.The dystocia occurred easier in the fetal macrosomia group than in the control group.The rate of cesarean section delivery was 72.91% in the macrosomia group,higher than 32.08% in control group.Conclusions: The antenatal care is reinforced during the pregnancy to prevent occurrence of the fetal macrosomia.The maternal weight,height,the gestational weeks at delivery,maternal abdominal circle,biparietal diameter and femur length are predictive factors for diagnosis of macrosomia.The best timing of labor and the best delivery pattern can to reduce the complications of mothers and infants.