Abstract: Objective: To observe the effect of fast track surgery(FTS) theory in perioperative nursing care for patients with lung cancer. Methods: A total of 60 cases of lung cancer were randomized divided into two groups. The control group received conventional nursing care and the experimental group adopted fast track surgery theory in perioperative nursing care. The incidence of post-operation pain,atelectasis,pleural effusion,lung infection,and the time of post-operative hospital stay and the total cost during hospitalization were compared between the two groups. Results: The VAS score of post operation pain at 24 hours,the incidence of atelectasis,the length of hospital stay after operation and the total cost decreased significantly in the experimental group when compared with that in the control group(P < 0.05-P < 0.01). There was no significant difference in the incidence of lung infection or pleural effusion between the two groups(P > 0.05). Conclusions: Application of FTS theory in perioperative nursing care could apparently accelerate the recovery of patients receiving lung cancer surgery,decrease the complication,shorten the time of hospital stay and cut down the total cost.